Download to PDF
Moist et al. studied the predictors of RRF loss in patients initiating either HD or PD using a national random sample of patients1. The predictors of RRF loss and adjusted odds ratios (AOR) are shown in the table.
|
Predictor
|
AOR
|
p value
|
|
Female
|
1.4
|
<0.001
|
|
Non-white
|
1.57
|
<0.001
|
|
History of diabetes
|
1.82
|
=0.006
|
|
History of CHF
|
1.32
|
=0.03
|
|
Time to follow-up (per month)
|
1.06
|
=0.03
|
PD patients had a 65% lower risk of RRF loss than those on HD (AOR = 0.35; p <0.001). Patients with higher serum calcium (AOR = 0.81 per mg/dl; p = 0.05), those who used an angiotensin-converting enzyme inhibitor (AOR = 0.68; p < 0.001), or who used a calcium channel blocker (AOR = 0.77; p = 0.01) were independently associated with decreased risk of RRF loss. An understanding of the demographic groups at risk and the factors and therapies that could potentially be modified allows one to prescribe therapies that may preserve RRF among ESRD patients.
Back to The Importance of RRF
Next
Reference:
-
Moist LM, Port FK, Orzol SM, Young EW, Ostbye T, Wolfe RA, Hulbert-Shearon T, Jones CA, Bloembergen WE. Predictors of loss of residual renal function among new dialysis patients. J Am Soc Nephrol 11:556-564, 2000